A compound having the structure of formula 3: ** Formula ** in which X is O or S； R1, R2, R3 and R4 are independently H, halogen, alkyl, alkoxy, aryloxy, thiol, alkylthiol, arylthiol, azido, amino, hydroxyl, sulfonyl, phosphonyl or boronic acid； or alkyl or alkoxy which are optionally substituted in turn one or more times with halogen, amino, hydroxyl, sulfonyl, phosphonyl, carbonyl or boronic acid； R10, R11 and R12 are independently H, halogen, alkyl, alkoxy, aryloxy, thiol, alkylthiol, arylthiol, azido, amino, hydroxyl, sulfonyl, phosphonyl, boronic acid L-RG or WSG； or alkyl or alkoxy which are optionally substituted in turn one or more times with halogen, amino, hydroxyl, sulfonyl, phosphonyl, carbonyl, boronic acid, L-RG or WSG； RG is a chemically reactive group that is acrylamide, amine, carboxylic acid, activated carboxylic acid ester, acylazide, acylnitrile, aldehyde, alkyl halide, anhydride, aryl halide, azide, aziridine, boronate, diazoalkane, halogenoacetamide, halogenotriazine , hydroxylamine, imidoester, isothiocyanate, maleimide, reactive platinum complex, sulfonyl halide or psoralen derivative； L is an optional linker that is null, alkyl, alkoxy, thioalkyl, amino acid, sulfoamino acid, polyamine, polyethylene glycol, aryl or heteroaryl； WSG is a water-soluble group that is sulfonate, thiosulfate, phosphonate, boronate, ammonium, pyridium, quinolium or acridium； at least one of R10, R11 and R12 contains L-RG； and at least one of R10, R11 and R12 is WSG.Un compuesto que tiene la estructura de fórmula 3:**Fórmula** en la que X es O o S； R1, R2, R3 y R4 son independientemente H, halógeno, alquilo, alcoxilo, ariloxilo, tiol, alquiltiol, ariltiol, azido, amino, hidroxilo, sulfonilo, fosfonilo o ácido borónico； o alquilo o alcoxilo que están sustituidos opcionalmente a su vez una o más veces con halógeno, amino, hidroxilo, sulfonilo, fosfonilo, carbonilo o ácido borónico； R10, R11 y R12 son independientemente H, halógeno, alquilo, alcoxilo, ariloxilo, tiol,
