mAb-driven chimeric antigen receptor systems for sorting/depleting engineered immune cells

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专利权人:

Rinat Neuroscience Corporation;Cellectis

发明人:

Sasu, Barbra Johnson,Rajpal, Arvind,Duchateau, Philippe,Juillerat, Alexandre,Valton, Julien

申请号：

AU2016212158

公开号：

AU2016212158A1

申请日:

2016.01.25

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

A polypeptide encoding a chimeric antigen receptor (CAR) comprising at least one extracellular binding domain that comprises a scFv formed by at least a VH chain and a VL chain specific to an antigen, wherein said extracellular binding domain comprises at least one mAb-specific epitope.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/