Hangzhou DAC Biotech Co., Ltd.;R. Yongxin Zhao;Yue Zhang;Yourang Ma
发明人:
R. Yongxin Zhao,Yue Zhang,Yourang Ma
申请号:
US14253881
公开号:
US10399941B2
申请日:
2014.04.16
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a Formula (I), wherein T, L, m, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, and R13 are defined herein, can be used for targeted treatment of cancer, autoimmune disease, and infectious disease.