FORMES CRISTALLINES DE CHLORHYDRATE DE MEDICAMENT EN VUE DU TRAITEMENT OU DE LA PREVENTION DE MALADIE ASSOCIEE A JAK ET METHODE DE PREPARATION ASSOCIEE

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专利权人:

CRYSTAL PHARMATECH CO.; LTD

发明人:

CHEN, MINHUA,ZHANG, YANFENG,LIU, KAI,ZHANG, XIAOYU

申请号：

CA3018610

公开号：

CA3018610A1

申请日:

2017.03.21

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Disclosed are a hydrochloride salt crystal of a drug (Filgotinib) for treating or preventing a JAK-associated disease and a preparation method, pharmaceutical composition, and formulation thereof, and an application of the hydrochloride salt crystal, the pharmaceutical composition, and the formulation in the prevention and/or treatment of a disease associated with a JAK family kinase. In comparison to a known crystal, the crystal provided in the invention shows more favorable properties in terms of pharmaceutical engineering, such as higher stability under low water activity conditions, simplicity in the preparation process and/or higher solubility.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/