PROBLEM TO BE SOLVED: To provide a medicine and a method contributing to a treatment for cancer by efficiently introducing into animal cells an antigen protein gene derived from a microorganism.SOLUTION: The complex includes: a vector encoding a gene of an antigen protein derived from a microorganism, for example, the antigen protein, ESAT-6, derived from Mycobacterium tuberculosis and a gene transfer reagent selected from cationic polymer, cationic lipid, and anionic polymer. The medicine and the method of treatment for cancer using the complex are also provided.COPYRIGHT: (C)2013,JPO&INPIT【課題】微生物由来抗原タンパク質遺伝子を効率的に動物細胞に導入し、医薬品および癌の治療に資する方法を提供する。【解決手段】微生物由来抗原タンパク質、例えば結核菌由来抗原タンパク質ESAT-6の、遺伝子をコードしたベクターと、カチオン性ポリマー、カチオン性脂質及びアニオン性ポリマーから選択される遺伝子導入試薬を含有する複合体。および該複合体を用いる医薬と、癌の治療方法。【選択図】なし