DE BRABANDER, JEF,ROSENBAUM, DANIEL,LIANG, QIREN,WANG, WENTIAN
申请号：
CA3095451
公开号：
CA3095451A1
申请日:
2019.03.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Methods and compositions for agonizing a type-2 orexin receptor (OX2R) in a cell determined to be in need thereof, including the general method of (a) administering to a subject a cyclic guanidinyl OX2R agonist and (b) detecting a resultant enhanced wakefulness or increased resistance to diet-induced accumulation of body fat, or abbreviated recovery from general anesthesia or jet lag.
