The Board of Regents of the University of Texas System
发明人:
Frolov, Ilya V.,Shustov, Alexandr V.
申请号：
AU2008248061
公开号：
AU2008248061B2
申请日:
2008.05.07
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention discloses a two-component genome flavivirus and a method for propagating such virus. Since the genetic material of this flavivirus is distributed between two genomes, the flavivirus is deficient in replication, incapable of causing disease but capable of inducing an immune response. Nevertheless, the design of the replication deficient flavivirus discussed herein allows propagation of these flaviviruses at industrial level.
