Westmead Institute For Medical Research;Western Sydney Local Health District;Icahn School of Medicine at Mount Sinai
发明人:
Barbara Murphy,Philip J. O'Connell
申请号:
US15810861
公开号:
US10725026B2
申请日:
2017.11.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A method for identifying a kidney transplant recipient at an increased risk of developing interstitial fibrosis or tubular atrophy which comprises obtaining a post-transplant urine sample from the kidney transplant recipient; measuring the level of clusterin in the urine sample; comparing the level of clusterin in the patient sample to the level of clusterin in a control sample from the urine of a non-fibrotic kidney transplant recipient; diagnosing a kidney transplant recipient with a clusterin level that is significantly higher than the clusterin level in the control as being at an increased risk of developing interstitial fibrosis or tubular atrophy.