The present invention can predict the occurrence of target-patient problem behavior prior the occurrence of such problem behavior. A biological information processing system includes: a feature calculation unit that calculates, from input biological information of the target patient, detection-use feature time-series data which indicates a feature related to the target patient: and an agitation detection unit that processes the detection-use feature time-series data on the basis of a pre-acquired discrimination parameter, that calculates the current agitation score of the target patient, and that detects the current agitation state of the target patient prior to the target-patient problem behavior.