Bv8 nucleic acids and polypeptides with mitogenic activity

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专利权人:

GENENTECH INC

发明人:

FERRARA NAPOLEONE,LECOUTER JENNIFER

申请号：

NO20040553

公开号：

NO332445B1

申请日:

2004.02.06

申请国别(地区):

NO

年份:

2012

代理人:

摘要：

The present invention provides methods of using Bv8 polypeptides to induce endothelial cell proliferation and to enhance endothelial cell survival. Also provided herein are methods of screening for modulators of Bv8 activity. Furthermore, methods of treatment using Bv8 polypeptides are provided.Den foreliggende oppfinnelsen tilveiebringer fremgangmåter for anvendelse av Bv8-polypeptider for å indusere endotelisk celledeling og for å forsterke endotelisk celleoverlevelse. Også tilveiebrakt heri er fremgangsmåter for å screene modulatorer av Bv8-aktivitet. Videre er det tilveiebrakt fremgangsmåter for behandling ved bruk av Bv8-polypeptider. Fig. 1 TGAGGGCGCCATGAGGAGCCTGTGCTGCGCCCCACTCCTGCTCCTCTTGCTGCTGCCGCC GCTGCTGCTCACGCCCCGCGCTGGGGACGCCGCCGTGATCACCGGGGCTTGTGACAAGGA CTCCCAATGTGGTGGAGGCATGTGCTGTGCTGTCAGTATCTGGGTCAAGAGCATAAGGAT TTGCACACCTATGGGCAAACTGGGAGACAGCTGCCATCCACTGACTCGTAAAAACAATTT TGGAAATGGAAGGCAGGAAAGAAGAAAGAGGAAGAGAAGCAAAAGGAAAAAGGAGGTTCC ATTTTTTGGGCGGAGGATGCATCACACTTGCCCATGTCTGCCAGGCTTGGCCTGTTTACG GACTTCATTTAACCGATTTATTTGTTTAGCCCAAAAGTAATCGCTCTGGAGTAGAAACCA AATGTGA

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/