Chimeric T cell receptor comprising carbonic anhydrase IX (G250) antibody

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专利权人:

发明人:

Wayne A. Marasco,Agnes Lo,Chen Xu

申请号：

US13889924

公开号：

US09676867B2

申请日:

2013.05.08

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.

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中国工程科技知识中心

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http://www.ckcest.cn/home/