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Pyrimidine compounds useful in the treatment of diseases mediated by IKKE and/or TBK1 mechanisms
专利权人:
DOMAINEX LIMITED
发明人:
Gary Karl Newton,Mark Richard Stewart,Trevor Robert Perrior,Stuart Richard Crosby,Anna Hopkins,Gabriel Negoita-Giras,Kerry Jenkins
申请号:
US14769421
公开号:
US09433622B2
申请日:
2014.02.21
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases associated with aberrant activity of the protein kinases IKKε and/or TBK-1 in which one of V and W is N, and the other of V and W is C—H; and R1, R2, R3 and R4 are as defined in the specification. The invention also provides uses of the compounds and compositions containing them.
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