LAW, CHE-LEUNG,WAHL, ALAN F.,SCHOLLER, NATHALIE,PESTANO, LINDA A.
申请号:
CA2516455
公开号:
CA2516455C
申请日:
2004.02.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated tocytotoxic, immunosuppressive, or other therapeutic agents, as well aspharmaceutical compositions and kits comprising the antibody- and antibodyderivative-drug conjugates. Also disclosed are methods, for the treatment ofCD70-expressing cancers and immunological disorders, comprising administeringto a subject the disclosed pharmaceutical compositions.