LAHOUTTE, TONY,DHUYVETTER, MATTHIAS,DE VOS, JENS,DEVOOGDT, NICK
申请号:
CA2991398
公开号:
CA2991398A1
申请日:
2016.07.15
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided herein are methods, kits, and compositions for stratifying and treating subjects, e.g., subjects having cancer. In some examples, the methods involve use of a radiolabelled heavy chain variable domain derived from a heavy chain antibody (VHH), or a functional fragment thereof, as both a screening agent and a treatment agent. In some examples, the VHH, or a functional fragment thereof, that is radiolabelled with a radioisotope that is both a ?-emitter and ß-emitter.