Joanne M. Smallheer,Ellen K. Kick,Meriah Neissel Valente,Carol Hui Hu,Oz Scott Halpern,Sutjano Jusuf
申请号：
US16099010
公开号：
US10577383B2
申请日:
2017.06.26
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides compounds of Formula (I): wherein the substituents are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, and may be useful for for the treatment and/or prophylaxis of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
