C.N.C.C.S. SCARL COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING;IRBM - SCIENCE PARK S.P.A.
发明人:
ALBERTO BRESCIANI,DANILO FABBRINI,EDITH MONTEAGUDO,EMANUELA NIZI,GIULIA BREVEGLIERI,PAOLA PACE,RALPH LAUFER,ROBERTO GAMBARI,SERGIO ALTAMURA,STEVEN HARPER,VINCENZO SUMMA
申请号:
BR112015002646
公开号:
BR112015002646A2
申请日:
2013.08.07
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention relates to compounds of formula (I) and (IV), and pharmaceutically acceptable salts, tautomers, stereoisomers thereof, which are inhibitors of histone deacetylase (HDAC). The compounds of the present invention are for use in the treatment of disorders that are ameliorated by inhibition of HDAC such as cancer and hemoglobinopathies like &bgr;-thalassemia or sickle cell anemia.