In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors

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专利权人:

Jonathan Wong;Lakshman R. Sehgal

发明人:

Lakshman R. Sehgal,Jonathan Wong

申请号：

US13023314

公开号：

US08367056B2

申请日:

2011.02.08

申请国别(地区):

US

年份:

2013

代理人:

摘要：

A method for treating a renal disease in a subject is disclosed. The method includes administering into a kidney of the subject with an effective amount of a gutless adenoviral vector containing a polynucleotide encoding a therapeutic agent. The gutless adenoviral vector contains the nucleotide sequence of SEQ ID NO:13 or SEQ ID NO:15 and expresses the therapeutic agent in a kidney tissue of the subject.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/