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NOUVELLE FORME CRISTALLINE D'INTERMÉDIAIRE DE DAPAGLIFLOZINE ET SON PROCÉDÉ DE PRÉPARATION
专利权人:
Jiangsu Hansoh Pharmaceutical Group Co.; Ltd.
发明人:
LI, Xiang,YU, Jun,YU, Haizhou,WANG, Jinjia,HE, Lei,DU, Zuyin
申请号:
EP17830500
公开号:
EP3489250A4
申请日:
2017.07.21
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Disclosed are a crystal form of a dapagliflozin intermediate and a preparation method therefor, and specifically disclosed are a crystal form of the dapagliflozin intermediate (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-ethoxy-6-(methylhydroxyl) tetrahydro-2H-pyran-3,4,5-triol and a preparation method therefor. The advantages thereof lie in that an intermediate can be highly purified to obtain a sample with a purity of 99.3% or more, wherein same has an important significance for improving the quality of the dapagliflozin, and the preparation process is simple and suitable for industrial production.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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