José Ignacio Andrés-Gil,Manuel Jesús Alcázar-Vaca,José Maria Cid-Núñez,Andrés Avelino Trabanco-Suárez,Guy Maurits R. Bormans,Sofie Jeanne Leopoldine Celen,Michel Koole
申请号:
US13884073
公开号:
US20130230459A1
申请日:
2011.11.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.