A new and distinct cultivar of Caladium plant named ‘;Splash Of Wine’;, characterized by its short, compact and mounding habit; dense and bushy appearance; vigorous growth habit and rapid growth rate; small fancy-type leaves that have dark green-colored venation with interveinal areas that are white flushed with red and light red in color and densely covered with red purple-colored spots and have narrow dark green-colored margins; and leaf petioles that are light red to light greyed orange and tinged with greyed red in color with dark greenish brown-colored stipples and streaks.