OLIGOMÈRES ET CONJUGUÉS ANTISENS CIBLANT PCSK9

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专利权人:

Roche Innovation Center Copenhagen A/S

发明人:

申请号：

EP19183357.3

公开号：

EP3591054A1

申请日:

2014.06.27

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to oligomeric compounds and conjugates thereof that target Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) PCSK9 mRNA in a cell, leading to reduced expression of PCSK9. Reduction of PCSK9 expression is beneficial for a range of medical disorders, such as hypercholesterolemia and related disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/