JI, MINGZHE,季明哲,BAI, HUA,白骅,白驊,LIU, LIFEI,刘礼飞,劉禮飛,GONG, YONGXIANG,龚永祥,龔永祥,LI, YI,李译,李譯,CAO, QIXIONG,曹启雄,曹啟雄,DENG, YONGXIAN,邓永先,鄧永先,CHAI, JIAN,柴健,LUO, HONGYING,骆红英,駱紅英
申请号:
TW106130048
公开号:
TW201811770A
申请日:
2017.09.01
申请国别(地区):
TW
年份:
2018
代理人:
摘要:
The present invention provides a dihydropyrimidine compound as shown in formula (I) or a pharmaceutically acceptable salt or tautomer or enantiomer or diastereomer thereof, wherein R1, R2, R3, R and A are as defined in the description and claims. The present invention also provides a method for preparing a compound of formula (I) and its use in a medicament for the treatment or prevention of hepatitis B virus infection.本發明提供一種如式(I)所示的二氫嘧啶類化合物或其可藥用鹽或互變異構體或鏡像異構體或非鏡像異構體,其中R1、R2、R3、R和A如說明書和申請專利範圍所定義。本發明還提供式(I)化合物的製備方法及其用於治療或者預防B型肝炎病毒感染的疾病的藥物中的用途。