Michael P. PIEPER;Thierry BOUYSSOU;Andreas SCHNAPP
发明人:
Thierry BOUYSSOU,Michael P. PIEPER,Andreas SCHNAPP
申请号：
US14071035
公开号：
US20140056823A1
申请日:
2013.11.04
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A pharmaceutical composition comprising:(a) a compound of formula 1wherein:n is 1 or 2；R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl；R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl； andR3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl,or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof； and(b) another active substance 2,wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
