President and Fellows of Harvard College;The Children's Medical Center Corporation
发明人:
Donald E. INGBER,Yusuke TORISAWA,Geraldine HAMILTON,Akiko MAMMOTO,Tadanori MAMMOTO,Catherine SPINA
申请号：
SG10201805199R
公开号：
SG10201805199RA
申请日:
2012.05.31
申请国别(地区):
SG
年份:
2018
代理人:
摘要：
METHODS AND USES FOR EX VIVO TISSUE CULT URE SYSTEMS The technology described herein is directed to methods and devices that can be used to induce functional organ structures to form within an implantation device by implanting it in vivo within the body of a living animal, and allowing cells and tissues to impregnate the 5 implantation device and establish normal microenvironmental architecture and tissue-tissue interfaces. Then the contained cells and tissues can be surgically removed intact and either transplanted into another animal or maintained ex vivo by perfusing it through one or more of the fluid channels with medium and/or gases necessary for cell survival. Figure 20A 10
