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ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ БЕТА-ЛАКТАМНЫЙ АНТИБИОТИК, СУЛЬБАКТАМ И ИНГИБИТОР БЕТА-ЛАКТАМАЗ
专利权人:
ВОКХАРДТ ЛИМИТЕД (IN)
发明人:
БХАГВАТ Сачин Субхаш (IN),ПАТЕЛ Махеш Витхалбхай (IN)
申请号:
RU2014106988/15
公开号:
RU2014106988A
申请日:
2011.10.04
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
A pharmaceutical composition comprising a pharmaceutically effective amount of: a) at least one beta-lactam antibiotic or a pharmaceutically acceptable salt thereof, b) a sulbactam or a pharmaceutically acceptable salt thereof, and c) at least one beta-lactamase inhibitor or a pharmaceutically acceptable salt thereof , provided that the inhibitor of beta-lactamases is not sulbactam. The pharmaceutical composition of claim 1, wherein the composition is in the form of a powder or solution. The pharmaceutical composition of claim 1, wherein the beta-lactam antibiotic or a pharmaceutically acceptable salt thereof is present in an amount of from about 0.01 g to about 10 g. The pharmaceutical composition of claim 1, wherein the sulbactam or a pharmaceutically acceptable salt thereof is present in an amount of from about 0.01 g to about 10 g. The pharmaceutical composition of claim 1, wherein the beta-lactamase inhibitor or a pharmaceutically acceptable salt thereof is present in an amount of from about 0.01 g to about 10 g. A method of preventing or treating a bacterial infection in an individual comprising administering to said individual a pharmaceutically effective amount of a pharmaceutical composition according to claim 1.7. A method of preventing or treating bacterial infection in an individual where said infection is caused by bacteria producing one or more beta-lactamase enzymes comprising administering to said individual a pharmaceutically effective amount of a pharmaceutical composition according to claim 1.8. The pharmaceutical composition of claim 1, wherein the beta-lactam antibiotic or a pharmaceutically acceptable salt thereof, a sulbactam or a pharmaceutically acceptable salt thereof, wherein the beta-lactamase inhibitor or a pharmaceutically acceptable salt thereof is present in an amount of from about 0.01 g to about 10 g. A method of preventing or treating a bacterial infection in an individual comprising administering to said individual a pharmaceutica
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