Matthew J. Callaghan;Christian S. Eversull;Stephen A. Leeflang
发明人:
Matthew J. Callaghan,Christian S. Eversull,Stephen A. Leeflang
申请号:
US14300179
公开号:
US20140364765A1
申请日:
2014.06.09
申请国别(地区):
US
年份:
2014
代理人:
摘要:
System and methods are provided for treating a patient that include a delivery device sized for introduction into a target site within a patient's body, a source of one or more therapeutic and/or diagnostic agents coupled to the delivery device, and a tubular member sized for introduction into the patient's vasculature to isolate the thoracic duct. Once the thoracic duct is isolated, fluid may be removed from the thoracic duct, e.g., to prevent the agents that transit from the target site into the thoracic duct from entering the patient's vasculature, and/or to modulate flow through the thoracic duct to modulate concentration and/or resident time of the agents at the target site. The one or more agents may include particles sized for preferential transit into the lymphatic system.