An imaging mini-scope (14) for use with an endoscope system (10) includes an elongated body (40) having a first length. The elongated body includes at least one passage (46) extending along the first length. A flexible distal tip portion (80) is coupled to the elongated body. An imaging device (60) includes an imaging sensor (62) disposed at the flexible distal tip portion and a signal transmission connection (64) extending through the at least one passage to connect the imaging sensor to a processing system. The imaging sensor is configured to detect image information and the signal transmission connection is configured to transmit one or more signals indicative of the detected image information from the imaging sensor to the processing system. A light source (70) is disposed at the flexible distal tip portion. The light source extends through the at least one passage.