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Pharmaceutical composition containing irbesartan
专利权人:
Gershon Kolatkar
发明人:
Gershon Kolatkar,Erela Zisman
申请号:
US13485493
公开号:
US08414920B2
申请日:
2012.05.31
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention relates to pharmaceutical compositions containing irbesartan, providing oral formulations with a high relative amount or concentration of irbesartan. In one embodiment, the present invention provides an oral formulation of irbesartan containing greater than 70% w/w irbesartan. In another embodiment, the invention provides an oral formulation of irbesartan which exhibits a dissolution profile according to which greater than about 85% of the Irbesartan is dissolved within about 30 minutes using USP apparatus 2, placing the tablet in 1000 mL of 0.1N hydrochloric acid at 37° C. with paddle speed of 50 rpm. The formulation can optionally contain at least one additional active ingredient.
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