A method for adjusting an output signal of a pulse diagnosis device includes obtaining a pulse signal at a pulse diagnosis region that is acquired by a sensing element of the pulse diagnosis device, and performing a parameter recognition on the pulse signal to obtain a parameter of the pulse signal, and determining a biological structure of the pulse diagnosis region based on the parameter of the pulse signal. The method also includes determining an adjustment factor for the parameter of the pulse signal based on the biological structure, and adjusting the parameter of the pulse signal based on the adjustment factor for the parameter of the pulse signal, to obtain an adjusted pulse signal for the pulse diagnosis region. The pulse signal is a pressure signal applied by an artery in the pulse diagnosis region to an external skin surface corresponding to the artery.