CHINESE ACADEMY OF SCIENCES;BEIJING INSTITUTE OF GENOMICS
发明人:
Yingli Sun,Lushuai Yao
申请号:
US15544735
公开号:
US20170362663A1
申请日:
2015.12.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed is a use of methylation sites as a disease diagnosis marker, in particular relating to a use of methylation sites in a Y chromosome as a prostate cancer diagnosis marker. More particularly, the method and criterion for screening methylation sites in chromosomes associated with a disease are established in the present invention, and using prostate cancer as an example, six methylation sites in the Y chromosome associated with the prostate cancer diagnosis are screened out. Methylation sites in the Y chromosome screened can be used for early and rapid diagnosis of the disease as a prostate cancer diagnosis marker.