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Synthetic bone graft biomaterial
专利权人:
Wei J. Lo
发明人:
Wei J. Lo
申请号:
US11273927
公开号:
US08288452B2
申请日:
2005.11.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A biomaterial comprising a ceramic material, the ceramic material having a plurality of connecting micropores of an average diameter of between 1 μm and 10 μm, substantially evenly distributed through the biomaterial. The ceramic particles are preferably partially fused to one or more adjacent ceramic particles to form a lattice defining micropores. Each particle preferably has an average diameter of 1 μm and 10 μm and may comprise a plurality of elongated macropores having an average diameter of between 150 μm and 500 μm. Further, the material may additionally contain midi-pores which are substantially spherical and have an average diameter of 5 μm and 150 μm. In addition, the application relates to a process for preparing a biomaterial comprising: (i) preparing a mixture of finely-divided biocompatible ceramic particles with a coating agent; (ii) causing the coating agent to coat the ceramic particles to form coated particles; (iii) causing the coated particles to form a body; and (iv) heating the body to eliminate residues of the coating agent, to partially fuse the ceramic particles and produce a fused biomaterial, and to biomaterials obtainable from the process and to the uses of the biomaterials.
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