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Crystals of phenylpyrrole derivatives
专利权人:
DAIICHI SANKYO COMPANY; LIMITED
发明人:
ONO, MAKOTO
申请号:
TW101114906
公开号:
TW201247659A
申请日:
2012.04.26
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The present invention provides monomethanesulfonate of phenylpyrrole derivatives, having excellent glucokinase activating activity, significantly improving solubility, hygroscopicity and stability, and exhibiting excellent oral absorption, and the crystal thereof. The present invention provides (2S) -2- (3- {5- [(5S) -5- Methyl -4, 5-dihydro-1, 3-oxazol-2-yl]-1H-pyrrol-2-yl}-5-{[5-(methylsulfonyl ) pyrazin-2-yl] oxy} phenoxy) propan-1-ol monomethanesulfonate, having excellent glucokinase activating activity, the crystal thereof, a medicine comprising them, and a prophylactic and/ or therapeutic agent for diabetes, etc.
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