A method of harvesting a blood vessel, the method may be performed by an apparatus which may include a flexible body portion (102) having at least one ultrasound transducer (112), the apparatus may be controlled by at least one controller, the method may include one or more acts of: percutaneously situating the flexible body into the blood vessel having vessel walls and connective tissue attached to the vessel walls； and exciting the at least one ultrasound transducer (112) to output ultrasound signals of a first type having a focal zone outside of the vessel walls so as to fractionate a region of connective tissue in the focal zone.
