Salim Merali,Camilo Moncada,Steven G. Kelsen,Carlos A. Barrero,Oscar Mauricio Perez Leal
申请号:
US14117157
公开号:
US09291626B2
申请日:
2012.05.11
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided is a method for diagnosing and/or staging COPD based on detection of one or more histone proteins. In some embodiments, the histone protein is an H3.3 protein comprising a post-translational modification. In some embodiments, the histone protein is H2B, H3, H3.3 or H4. Kits for practicing the methods of diagnosis and/or staging are provided as well. Further provided is a method for treating COPD.