BOLIN DAVID R,CHEUNG ADRIAN WAI HING,HHAMILTON MATTHEW MICHAEL,MARCOPULOUS NICHOLAS,MCDERMOTT LEE APOSTLE,QIAN YIMIN
申请号:
IN3482/DELNP/2011
公开号:
IN2011DN03482A
申请日:
2011.05.11
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
were RI is phenyl, R2 is hyrogen, halogen or lower alkyl ,X is carbon on nitrogen,and R3 is isoquinoline,-amino, or a-4- to 6-membered heterocycloalkyl ring and pharmaceutically acceptable salts thereof, which are active as DGAT inhibitors and therefore find uses in treatment of diseases associated with abnormal metabolism of triglicerides, such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.