DERIVADOS DE 6,7,8,9-TETRAHIDRO-5H-PIRIMIDO[4,5-D]AZEPINA-4-IL]-AMINA COMO MODULADORES DE TRPV1 PARA O TRATAMENTO DA DOR

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专利权人:

JANSSEN PHARMACEUTICA N.V.

发明人:

BRETT D. ALLISON,MICHAEL D. HACK,BRYAN JAMES BRANSTETTER,JAMES GUY BREITENBUCHER,NATALIE A. HAWRYLUK,ALEC D. LEBSACK,KELLY J. MCCLURE,JEFFREY E. MERIT

申请号：

PT07753768

公开号：

PT2024368E

申请日:

2007.03.21

申请国别(地区):

PT

年份:

2014

代理人:

摘要：

Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by TRPV1. Thus, the compounds may be administered to treat, e.g., pain, itch, cough, asthma, or inflammatory bowel disease.

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