The present invention is related to methods and compositions for the therapeuticand diagnostic use in the treatment of diseases and disorders which are causedby or associated with amyloid or amyloid-like proteins including amyloidosis.In particular, the present invention provides methods and compositions foreliciting a highly specific and highly effective immune response in an organism,but particularly within an animal, particularly a mammal or a human, which iscapable of preventing or alleviating amyloidosis, or the symptoms associatedwith amyloidosis, a group of diseases and disorders associated with amyloidplaque formation including secondary amyloidosis and age-related amyloidosisincluding, but not limited to, neurological disorders such as Alzheimer's Disease (AD) , including diseases or conditions characterized by a loss of cognitivememory capacity such as, for example, mild cognitive impairment (MCI) .
