Chung-Ang University Industry Academic Cooperation Foundation
发明人:
Kisung Ko,Deuk-su Kim,Kinarm Ko
申请号：
US15376031
公开号：
US20170159066A1
申请日:
2016.12.12
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to a method for manufacturing a transgenic plant producing immunogenic complex proteins and immunogenic complex proteins obtained therefrom and, more specifically, to a method for manufacturing a transgenic plant producing immunogenic complex proteins, a plant manufactured by the method, and immunogenic complex proteins obtained from the plant, wherein the method comprises the steps of: (a) manufacturing a transgenic plant expressing an antigen； (b) manufacturing a transgenic plant expressing an antibody specific to the antigen in step (a)； and (c) cross-breeding the plants in steps (a) and (b) to manufacture a cross-bred plant. Immunogenic complex proteins can be mass-produced through the method for manufacturing a transgenic plant, comprising steps (a) to (c), and the transgenic plant manufactured by the method, of the present invention. Further, the immunogenic complex proteins (antigen-antibody complex) obtained from the plant have a gigantic four-dimensional structure, thereby having an excellent immune reaction boosting effect, thus exhibiting an excellent antibody producing capacity in a host animal, even without the use of an immune adjuvant.
