PROBLEM TO BE SOLVED: To provide a particle comprising a polypeptide and at least one antigen, and a composition comprising the same.SOLUTION: The polypeptide includes at least one first attachment site, and the at least one antigen includes at least one second attachment site. The polypeptide and the antigen are linked through the at least one first attachment site and the at least one second attachment site. The spatial distance between the N-terminal residue and C-terminal residue of the antigen is 30 Å or less when measured in a crystal of the antigen or a naturally occurring protein containing the antigen or modified protein therefrom.SELECTED DRAWING: None【課題】ポリペプチドと少なくとも１つの抗原とを含む粒子ならびにそれを含む組成物の提供。【解決手段】前記ポリペプチドが少なくとも１つの第一付着部位を含み、少なくとも１つの前記抗原が少なくとも１つの第二付着部位を含み、前記ポリペプチド及び前記抗原が、かかる少なくとも１つの第前記一付着部位及び前記第二付着部位を介して結合し、前記抗原のＮ－末端残基とＣ－末端残基の間の空間距離が、前記抗原又は前記抗原を含む天然起源の蛋白質又はその修飾蛋白質の結晶で測定した場合に30Å以下である、前記粒子。【選択図】なし
