Michael Lee Roukes,Ronald James Cotton,Laurent Moreaux,Kenneth Shepard,Athanassios Siapas,Andreas Tolias
申请号：
US14534163
公开号：
US20160150963A1
申请日:
2014.11.05
申请国别(地区):
US
年份:
2016
代理人:
摘要：
An apparatus and method for detecting functional cellular activity within a volume of a tissue. The method includes inserting a three-dimensional array of optical emitters and optical detectors into a volume of a tissue, where the tissue volume includes one or more cells labeled with an optical reporter of cellular activity illuminating the one or more cells with photons from the optical emitters of the three-dimensional array to generate optical signals from the optical reporter that labels the one or more cells and detecting the optical signals using the optical detectors of the three-dimensional array, where the illumination includes one-photon excitation of the optical reporter.
