The present invention provides a centrifugal separator (14) for separation of at least two components of a fluid mixture which are of different densities. The centrifugal separator (14) comprises a stationary frame (15), a spindle (16) rotatably supported by the frame, a centrifuge rotor 17 mounted to a first end of the spindle to rotate together with the spindle around an axis (X2) of rotation, wherein the centrifuge rotor comprises a rotor casing enclosing a separation space (18) in which a stack (10) of separation discs (1) is arranged to rotate coaxially with the centrifuge rotor, a separator inlet (29) extending into said separation space for supply of the fluid mixture to be separated, a first separator outlet (33) for discharging a first separated phase from said separation space, a second separator outlet (34) for discharging a second separated phase from said separation space. The stack of separation discs comprises a set of axially aligned separation discs having a truncated conical shape with an inner surface and an outer surface and comprising a plurality spot-formed spacing members extending from a base from at least one of the inner surface and the outer surface for providing interspaces between mutually adjacent separation discs. The of separation discs comprises at least 200 separation discs having a diameter of at least 300 mm, and the surface density of said spot-formed spacing members is above 25 spot-formed spacing members/dm2 throughout the inner and/or outer surface of the separation disc.