Systems, methods and devices are provided for improving data management between implantable medical devices (IMDs) and external devices for the detection of volume overload and volume depletion conditions. Data acquired by the IMD is periodically communicated to the external device where a volume overload monitoring algorithm is operated to detect whether a volume overload condition is present in the patient by monitoring the acquired data at the external device at a first lower, non-real-time frequency rate. Upon detection of a volume overload condition, the external device issues an instruction to the IMD causing the IMD to initiate a volume depletion condition monitoring algorithm for detecting in real time whether a volume depletion condition is present in the patient.