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Antigen-bindng constructs
专利权人:
GLAXO GROUP LIMITED
发明人:
CLAIRE ASHMAN,THIL BATUWANGALA,MICHAEL NEIL BURDEN,STEPHANIE JANE CLEGG,RUDOLF MARIA DE WILDT,JONATHAN ELLIS,PAUL ANDREW HAMBLIN,FARHANA HUSSAIN,LAURENT JESPERS,ALAN LEWIS,MARTIN ANIBAL ORECCHIA,RADHA
申请号:
GB201008468
公开号:
GB2468232B
申请日:
2008.11.28
申请国别(地区):
GB
年份:
2012
代理人:
摘要:
The invention relates to antigen-binding constructs comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding construct has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof.
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