SINCLAIR, Steven Michael,DANILKOVITCH, Alla,SATHYAMOORTHY, Malathi,KUANG, Jin-Qiang,DHALL, Sandeep,MELCHIORRI, Anthony John
申请号:
EP17816341
公开号:
EP3474665A4
申请日:
2017.06.23
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Disclosed are methods of lyophilizing a tissue sample comprising obtaining a tissue sample, contacting the tissue sample with a lyoprotectant solution, freezing the tissue sample, performing a first drying step of the tissue sample after freezing, and performing a second drying step of the tissue sample after the first drying step. Disclosed are lyophilized tissues prepared using the disclosed methods of lyophilizing a tissue sample comprising obtaining a tissue sample, contacting the tissue sample with a lyoprotectant solution, freezing the tissue sample, performing a first drying step of the tissue sample after freezing, and performing a second drying step of the tissue sample after the first drying step. Disclosed are methods of treating a wound or tissue defect comprising administering a reconstituted lyophilized tissue to the wound or tissue defect.