Edible Plants Producing Bioengineered Micro-RNA for Gene Regulation Upon Ingestion

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专利权人:

发明人:

Vicki Vance,Keith Lynn Wycoff

申请号：

US15443279

公开号：

US20170246321A1

申请日:

2017.02.27

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Methods and materials providing a route for the use of transgenic plants as bio-factories to produce therapeutic miRNAs are described. The plants can be ingestible and can be used to deliver to a subject in need thereof a therapeutic miRNA by ingestion of the bioengineered plant tissue that carries an exogenous genetic sequence for the therapeutic miRNA. The therapeutic miRNA can be useful in treating a disease state such as cancer. The therapeutic miRNA can be a mammalian tumor suppressor miRNA.

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