Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators

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专利权人:

Beigene; Ltd.

发明人:

Zhiwei Wang,Yunhang Guo

申请号：

US14723417

公开号：

US09447106B2

申请日:

2015.05.27

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The invention is substituted 4,5-dihydro- and 4,5,6,7-tetrahydro-pyrazolo[1,5-α]pyrimidine compounds of formula (I),and salts thereof, compositions thereof, and methods of use therefor, such as inhibiting protein kinase, including Bruton's tyrosine kinase (Btk), and for treating disorders mediated thereby.

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