23-substituted bile acids as TGR5 modulators and methods of use thereof

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专利权人:

Intercept Pharmaceuticals; Inc.

发明人:

Pellicciari, Roberto

申请号：

AU2008209566

公开号：

AU2008209566C1

申请日:

2008.01.18

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The invention relates to compounds of Formula A: (A) or a pharmaceutically acceptable salt,solvate, hydrate, or prodrug thereof. The compounds of Formula A are TGR5 modulatorsuseful for the treatment of various diseases, including obesity, insulin sensitivity,inflammation, cholestasis, and bile desaturation.

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