KYI, Stanley,HAVNER, Robert,HASSANEIN, Waleed,KHAYAL, Tamer,SALEH, Hesham,FATTAH, Ihab Abdel,TRACHTENBERG, Jon
申请号：
ES07755790
公开号：
ES2625850T3
申请日:
2007.04.19
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A method of maintaining an ex vivo lung (1004), comprising: providing a lung care system (1000) comprising a perfusion circuit, connecting the lung (1004) within the fluid perfusion circuit, connecting the lung ( 1004) through a tracheal interface (1024) to a respirator； flow a perfusion fluid into the lung (1004) through a pulmonary artery interface (1022) and out of the lung (1004) through a pulmonary vein interface (1026), ventilate the lung (1004) to through the tracheal interface (1024) with the respirator, thereby providing a respiratory gas to the lung (1004) for use in the metabolism by the lung (1004), the respiratory gas having a predetermined oxygen composition, measuring a level of a gradient of arteriovenous oxygen (AV) between the perfusion fluid that flows into the lung and that flows out of the lung, characterized by after reaching an equilibrium state of the system (1000) where the perfusion fluid flowing inside the lung (1004) includes a first gaseous component to a first substantially constant composition and the perfusion fluid flowing out of the lung (1004) includes the first gaseous component to a second composition On substantially constant, continue perfusing the lung (1004) for a prolonged period of time in said equilibrium state.Un procedimiento para mantener un pulmón (1004) ex vivo, que comprende: proporcionar un sistema de cuidado de pulmones (1000) que comprende un circuito de perfusión, conectar el pulmón (1004) dentro del circuito de perfusión de fluido, conectar el pulmón (1004) a través de una interfaz traqueal (1024) a un respirador； hacer fluir un fluido de perfusión al interior del pulmón (1004) a través de una interfaz de arteria pulmonar (1022) y fuera del pulmón (1004) a través de una interfaz de vena pulmonar (1026), ventilar el pulmón (1004) a través de la interfaz traqueal (1024) con el respirador, proporcionando de este modo un gas respiratorio al pulmón (1004) para uso en el metabolismo por el pulmón (1004), teniendo el g
