ANTHONY EAMON STOREY,CLARE LOUISE JONES,DENIS RAYMOND CHRISTOPHE BOUVET,NICOLAS LASBISTES,STEVEN MICHAEL FAIRWAY,LORENZO WILLIAMS,ALEXANDER MARK GIBSON,ROBERT JAMES NAIRNE,FARHAD KARIMI,BENGT LANGSTRO
申请号：
HK13104661.5
公开号：
HK1177463B
申请日:
2013.04.17
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The invention relates to a process for preparation of a compound of formula (I): R1 is selected from C1-6alkyl, C2-6alkenyl, and C2-6alkynyl； which comprises: (i) reaction with fluoride, suitably [18F]fluoride, of a corresponding compound of formula (II): wherein R2 is selected from hydrogen, C1-10alkyl, C1-10haloalkyl, C6-14aryl, C6-14arylalkyl, &mdash；(CH2CH2O)q&mdash；CH3 wherein q is an integer of from 1 to 10； R1 is as defined for the compound of formula (I)； and R3 is a leaving group. Certain novel precursors of formula (II) and radiopharmaceutical kits containing such precursors are also claimed.
