The invention concerns novel DNA and amino acid sequences of monoclonalantibodies (mAbs) raised against lymphoblastoid cells and peptides to whichthe mAbs bind to. The invention also concerns diagnostic assays using saidantibodies or peptides for detecting individuals with a high probability ofhaving a malignant disease and, at times, for detecting an individual having aspecific malignant disease. The invention further concerns pharmaceuticalcompositions comprising the mAbs or peptides of the invention for use in thetreatment of various malignant diseases as well as methods for the treatmentof malignant diseases using the mAbs or peptides of the invention.